ORAL-ADMINISTRATION OF MONENSIN AND LEAD TO BROILER CHICKS - EFFECTS ON HEMATOLOGICAL AND BIOCHEMICAL PARAMETERS

Monensin and lead were administered separately or concurrently at diff erent toxic doses to broiler chicks. Administration of lead alone did not result in a significant depression of haematological parameters. A dministration of higher levels of monensin caused a reduction in haema tocrit and an increase in blood serum levels of alanine aminotransfera se, aspartate aminotransferase and cholesterol. Concurrent administrat ion of monensin and lead caused a severe depression of haematological profiles which indicated the existence of an interaction between the t wo substances. It was concluded that concurrent administration of mone nsin and lead potentiated the toxic effects of each other.