CLINICAL AND STRUCTURAL-METABOLIC CHARACT ERISTICS OF ATROPHIC FORMS OF CHRONIC-BRONCHITIS

A clinical-morphological study of bronchobiopsies from 78 patients wit h endoscopic picture of atrophic endobronchitis was carried out. Two f orms of morphogenesis of chronic' atrophic process in the bronchial mu cosa are distinguished: primary dystrophic and primary inflammatory. P rimary dystrophic bronchopathy is a clinical manifestations of the fir st form which presents structurally and functionally as primary dystro phy and atrophy of the bronchial mucosa in combination with sclerosis of the lamina proproae in a sharp decrease of synthetic processes in b ronchial, epitheliocytes as indicated by the data of autoradiography. The primary inflammatory form of atrophic process has clinical symptom s typical for inflammatory process and is characterized by gradual reo rganization in the bronchial wall and by maintaining sufficiently high level of metabolic reactions in bronchial epitheliocytes.