THE SYNTHESIS OF BRL-49653 - A NOVEL AND POTENT ANTIHYPERGLYCEMIC AGENT

Authors
CANTELLO BCC CAWTHORNE MA HAIGH D HINDLEY RM SMITH SA THURLBY PL
Citation
Bcc. Cantello et al., THE SYNTHESIS OF BRL-49653 - A NOVEL AND POTENT ANTIHYPERGLYCEMIC AGENT, Bioorganic & medicinal chemistry letters, 4(10), 1994, pp. 1181-1184
Citations number
23
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
4
Issue
10
Year of publication
1994
Pages
1181 - 1184
Database
ISI
SICI code
0960-894X(1994)4:10<1181:TSOB-A>2.0.ZU;2-V
Abstract
Modifications based upon a metabolite of ciglitazone afforded BRL 4965 3, a novel potent insulin sensitizer. A facile synthesis of this compo und is described.