THE MEIOTIC PAIRING BEHAVIOR IN HUMAN SPERMATOCYTES CARRIER OF CHROMOSOME-ANOMALIES AND THEIR REPERCUSSIONS ON REPRODUCTIVE FITNESS .1. INVERSIONS AND INSERTIONS - A EUROPEAN COLLABORATIVE STUDY

Authors
GABRIELROBEZ O RUMPLER Y BATANIAN J CHANDLEY AC COUTURIER J CROQUETTE MF DELAFONTAINE D GOLDMAN A GUICHAOUA MR HARGREAVE TB HULTEN MA JOHANNISSON R LEMAREC B LUCIANI JM MCBEATH S DEPERDIGO A RATOMPONIRINA C RIGOT JM SAADALLAH N TAILLEMITE JL SPEED RM YORTON L
Citation
O. Gabrielrobez et al., THE MEIOTIC PAIRING BEHAVIOR IN HUMAN SPERMATOCYTES CARRIER OF CHROMOSOME-ANOMALIES AND THEIR REPERCUSSIONS ON REPRODUCTIVE FITNESS .1. INVERSIONS AND INSERTIONS - A EUROPEAN COLLABORATIVE STUDY, Annales de genetique, 37(1), 1994, pp. 3-10
Citations number
26
Categorie Soggetti
Genetics & Heredity
Journal title
Annales de genetique → ACNP
ISSN journal
00033995
Volume
37
Issue
1
Year of publication
1994
Pages
3 - 10
Database
ISI
SICI code
0003-3995(1994)37:1<3:TMPBIH>2.0.ZU;2-B
Abstract
The synaptic behavior of pachytene chromosomes was studied in men hete rozygous for inversions and one inversion-insertion by analysis of syn aptonemal complexes at the electron microscopy level. The human meioti c data were collected from European laboratories in order to test the current theories and to link the arrest of spermatogenesis and the ris k of chromosome imbalance to the mode of pairing and their consequence s. The breakpoint location would allow to predict the synaptic and rec ombinational behavior of chromosome aberrations and particularly the r isk of aneusomie de recombinaison in the progeny of inversion carriers .