Background: The authors report four cases of conjunctival epithelial i
nvasion into the fibrous capsule surrounding a Baerveldt glaucoma impl
ant. All cases were associated with concurrent or recent prior scleral
buckling surgery. Methods: Three patients had postoperative conjuncti
val wound leaks, one in the immediate postoperative period and the oth
er two at 9 and 17 days postoperatively after release of the tube liga
ture. In the fourth patient, a fistulous tract developed over the impl
ant after a first-stage insertion. Histopathologic confirmation of sub
conjunctival epithelialization was obtained in two of these patients.
Results: Surgical revision was performed in all patients. Excision and
debridement of all epithelium-lined subconjunctival tissues and exten
sive bipolar cautery were used in the three patients with wound leaks.
Implant removal also was performed in one of these. Fistulectomy and
bipolar cautery were used in the fourth patient. No recurrent wound le
aks or other adverse sequelae were noted. Conclusions: Epithelial inva
sion of the subconjunctival space and inner bleb wall after implantati
on of glaucoma drainage devices can lead to breakdown of the conjuncti
val wound and persistent aqueous leak. Prior or concurrent scleral buc
kling surgery may predispose to this occurrence. Surgical revision inv
olving epithelial debridement, cautery, and meticulous wound closure,
with or without implant removal, has been used successfully in the man
agement of this complication.