VISUALIZATION OF AN EFFERENT PROJECTION ROUTE OF THE HYPOTHALAMIC RATARCUATE NUCLEUS THROUGH THE STRIA TERMINALIS AFTER LABELING WITH CARBOCYANINE DYE (DII) OR PROOPIOMELANOCORTIN-IMMUNOHISTOCHEMISTRY
R. Magoul et al., VISUALIZATION OF AN EFFERENT PROJECTION ROUTE OF THE HYPOTHALAMIC RATARCUATE NUCLEUS THROUGH THE STRIA TERMINALIS AFTER LABELING WITH CARBOCYANINE DYE (DII) OR PROOPIOMELANOCORTIN-IMMUNOHISTOCHEMISTRY, Neuroscience letters, 172(1-2), 1994, pp. 134-138
The hypothalamic arcuate nucleus is known to be reciprocally connected
to various limbic regions, such as the bed nucleus of the stria termi
nalis (BST). The route of this reciprocal connection, in particular wi
th the BST, remains unknown. In order to visualize this pathway, we us
ed the fluorescent tracer carbocyanine dye (DiI), that was inserted in
the arcuate nucleus in fixed and dissected brains. This allowed us to
label an arcuate-BST pathway DiI-labeled coursing through the stria t
erminalis. Immunohistochemistry for the arcuate-derived peptide adreno
cortico-tropin (ACTH) revealed the presence of ACTH-immunoreactive axo
ns in the stria terminalis. Together, these results provide arguments
in favour of the existence of an arcuatofugal projection to the BST vi
a the stria terminalis.