A BIOASSAY FOR THE DETECTION OF TUMOR-NECROSIS-FACTOR FROM 8 DIFFERENT SPECIES - EVALUATION OF NEUTRALIZATION RATES OF A MONOCLONAL-ANTIBODY AGAINST HUMAN TNF-ALPHA

Authors
PAULI U BERTONI G DUERR M PETERHANS E
Citation
U. Pauli et al., A BIOASSAY FOR THE DETECTION OF TUMOR-NECROSIS-FACTOR FROM 8 DIFFERENT SPECIES - EVALUATION OF NEUTRALIZATION RATES OF A MONOCLONAL-ANTIBODY AGAINST HUMAN TNF-ALPHA, Journal of immunological methods, 171(2), 1994, pp. 263-265
Citations number
4
Categorie Soggetti
Immunology
Journal title
Journal of immunological methods → ACNP
ISSN journal
00221759
Volume
171
Issue
2
Year of publication
1994
Pages
263 - 265
Database
ISI
SICI code
0022-1759(1994)171:2<263:ABFTDO>2.0.ZU;2-H
Abstract
We have evaluated a recently developed bioassay based on porcine kidne y (PK(15)) cells for the detection of tumor necrosis factor-alpha (TNF -alpha) from eight different species. This test could also be used to measure human TNF-beta with similar sensitivity when compared to the w idely used L929 bioassay.