CONFIGURATIONAL STABILITY OF CHIRAL ORGANOLITHIUM COMPOUNDS ON THE TIME-SCALE OF THEIR ADDITION TO ALDEHYDES

Authors
HOFFMANN RW JULIUS M CHEMLA F RUHLAND T FRENZEN G
Citation
Rw. Hoffmann et al., CONFIGURATIONAL STABILITY OF CHIRAL ORGANOLITHIUM COMPOUNDS ON THE TIME-SCALE OF THEIR ADDITION TO ALDEHYDES, Tetrahedron, 50(20), 1994, pp. 6049-6060
Citations number
40
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
50
Issue
20
Year of publication
1994
Pages
6049 - 6060
Database
ISI
SICI code
0040-4020(1994)50:20<6049:CSOCOC>2.0.ZU;2-G
Abstract
A test based on kinetic resolution has been applied to the alpha-bromo -, alpha-phenylseleno- and alpha-phenylthio-alkyl-lithium compounds 1, which shows that addition of these species to the chiral aldehyde 6 o ccurs faster than enantiomer equilibration of the organolithium compou nds.