We study the thinning by evaporation of completely wetted water films
on clean mica surfaces in a pure water vapor environment. In the thick
ness range from 100 to approximately 1000 angstrom the thinning is uns
table to nucleation of dry patches, and the spreading of these patches
invokes a ''de-wetting'' of the substrate. The initial process is des
cribed by a simple nucleation theory. A number of hydrodynamic effects
and instabilities are also observed at the boundary of the film.