Ro. Parra et al., THE VALUE OF LAPAROSCOPIC LYMPHADENECTOMY IN CONJUNCTION WITH RADICALPERINEAL OR RETROPUBIC PROSTATECTOMY, The Journal of urology, 151(6), 1994, pp. 1599-1602
A total of 76 men with clinically localized prostate cancer underwent
surgical treatment at our institution during an ii-month period. Of th
e patients 26 underwent staging laparoscopic pelvic lymph node dissect
ion followed by radical perineal prostatectomy (group 1), 24 underwent
laparoscopic pelvic lymph node dissection and radical retropubic pros
tatectomy (group 2), and 26 underwent standard open lymphadenectomy an
d radical retropubic prostatectomy (group 3). Group 1 patients experie
nced statistically significantly less average blood loss (576 +/- 360
cc) than either group 2 (1,275 +/- 686.8) or 3 (1,100 +/- 459, p <0.00
1). Hospital stay was also significantly less in group 1, with a mean
of 4.6 +/- 1.9 days compared to 9.6 +/- 4.6 and 7.25 +/- 2.06 days for
groups 2 and 3, respectively (p <0.001). Our study supports the combi
nation of laparoscopic pelvic lymph node dissection and radical perine
al prostatectomy as a potentially less morbid approach to the surgical
treatment of prostate cancer. However, no benefit was found for lapar
oscopic staging in patients before radical retropubic prostatectomy.