E. Erturk et al., BILATERAL ACETYLSULFAPYRIDINE NEPHROLITHIASIS ASSOCIATED WITH CHRONICSULFASALAZINE THERAPY, The Journal of urology, 151(6), 1994, pp. 1605-1606
We report on formation of bilateral renal calculi secondary to sulfasa
lazine therapy for juvenile rheumatoid arthritis. The condition was su
ccessfully treated with extracorporeal shock wave lithotripsy. Analysi
s of the fragments with thin layer chromatography and nuclear magnetic
resonance revealed acetylsulfapyridine, a metabolite of sulfasalazine
.