AN EXTREMELY LARGE, CAULIFLOWER-TYPE, CUTANEOUS METASTASIS OF OVARIAN-CANCER ASSOCIATED WITH GOOD PROGNOSIS

We report an unusual case of a 37-year-old woman who presented in 1980 with a serous papillary cystadenocarcinoma of the ovary. The patient refused any treatment and the patient was lost to follow-up for 6 year s. After this period of time she returned with an extremely large, cut aneous, cauliflower-type of metastasis located in the lower abdominal wall and measuring 20 x 20 cm. She received two courses of chemotherap y treatment consisting of intraperitoneal cisplatin (100 mg/m2) and in travenous epirubicin (50 mg/m2) every 3 weeks. After the second course of chemotherapy she received cobalt radiotherapy (5000 cGy). Subseque ntly, she received four more courses of chemotherapy with dramatic rem ission of the cutaneous metastasis. Shortly after chemotherapy, the pa tient underwent a laparotomy consisting of the resection of the abdomi nal wall including the cutaneous metastasis completed by total abdomin al hysterectomy, bilateral salpingo-oophorectomy, and omentectomy. The patient is well after the surgery and without any evidence of residua l disease after 6 years of follow up. This description illustrates a r are example of ovarian cancer with skin metastases and favorable outco me. (C) 1994 Academic Press, Inc.