Epithelial ovarian cancer is the most common cause of death due to gyn
ecologic malignancies in adults, but is rare in children and adolescen
ts. The majority of ovarian cancers in children and adolescents are st
age I at diagnosis and conservative management with preservation of fe
rtility is often possible. Twenty-nine serous epithelial cancers have
been reported in females under age 20, only two of which are known to
be advanced stage (both stage III). We present a case of advanced stag
e papillary serous cystadenocarcinoma in a 15-year-old female treated
with bilateral salpingo-oophorectomy and debulking surgery followed by
combination chemotherapy. (C) 1994 Academic Press, Inc.