LOW-RESOLUTION X-RAY-DIFFRACTION DATA OBTAINED FROM HEXAGONAL CRYSTALS OF METHYLAMINE-TREATED ALPHA(2)-MACROGLOBULIN

Two hexagonal crystal forms of tetrameric human methylamine-treated al pha2-macroglobulin have been grown by vapour diffusion. One of the cry stal forms diffracts X-rays beyond 9 angstrom resolution. The space gr oup of this form is P6(2)22 or P6(4)22 with a = b = 327, c = 219 angst rom and with one dimer Of alpha2-macroglobulin in the asymmetric unit. Several data sets have been collected by the use of synchrotron radia tion at cryogenic temperature. A native data set extending to 10 angst rom resolution has been obtained. The merging R factor of these data i s 10.3%.