Doppler flow velocity waveforms from fetal cerebral vessels can be rel
iably obtained by a transabdominal or transvaginal scanning route. Cha
nges in pulsatility imply alterations in cerebral impedance and reflec
t the physiological regulatory mechanisms underlying pathological proc
esses during pregnancy. In fetuses severely distressed due to failure
of placental function, the ratios reflecting the redistribution of fet
al circulation (e.g. the 'brain-sparing effect') help to identify fetu
ses at risk for fetal hypoxia. Apart from providing an increase in med
ical knowledge, this non-invasive technique is proving to be clinicall
y useful.