M. Hujanen et Yy. Linko, OPTIMIZATION OF L(-LACTIC ACID PRODUCTION EMPLOYING STATISTICAL EXPERIMENTAL-DESIGN()), Biotechnology techniques, 8(5), 1994, pp. 325-330
An Orthogonal 2(3)-factorial experimental design was used to optimize
L(+)-lactic acid production by Lactobacillus casei. With a 22 % (v/v)
inoculum the optimum concentration of yeast extract for maximum lactic
acid concentration and yield was about 2 % (w/v) and that of the init
ial glucose 9 to 11 %.