Lt. Dunn et Pm. Foy, ANTICONVULSANT AND ANTIBIOTIC-PROPHYLAXIS IN HEAD-INJURY, Annals of the Royal College of Surgeons of England, 76(3), 1994, pp. 147-149
The evidence for and against the prophylactic use of anticonvulsants a
nd antibiotics in head injury is reviewed. There is a lack of blinded
placebo-controlled trials in this area. On balance there is no compell
ing evidence to support the use of either anticonvulsant or antibiotic
prophylaxis in head injury, with the possible exception of antibiotic
prophylaxis in compound depressed skull fractures and penetrating bra
in injuries.