INVERSION (14)(Q11Q32) IN CHILDHOOD T-CELL ACUTE LYMPHOBLASTIC-LEUKEMIA

Authors
KWONG YL SHING MK WAN TM YUEN PMP CHAN AYY WONG KF CHAN LC
Citation
Yl. Kwong et al., INVERSION (14)(Q11Q32) IN CHILDHOOD T-CELL ACUTE LYMPHOBLASTIC-LEUKEMIA, Cancer genetics and cytogenetics, 72(2), 1994, pp. 92-95
Citations number
23
Categorie Soggetti
Oncology,"Genetics & Heredity
Journal title
Cancer genetics and cytogenetics → ACNP
ISSN journal
01654608
Volume
72
Issue
2
Year of publication
1994
Pages
92 - 95
Database
ISI
SICI code
0165-4608(1994)72:2<92:I(ICTA>2.0.ZU;2-X
Abstract
Inversion (14)(q11q32) is a common cytogenetic aberration in T-cell ch ronic lymphoid malignancies but is rare in T-cell acute lymphoblastic leukemia (T-ALL). We describe two cases of childhood T-ALL in which in v(14)(q11q32) was present concomitantly with other karyotypic aberrati ons typical of T-ALL. The possible significance of inv(14) in these ca ses is also discussed.