Although the causes of population extinction, locally and globally, ar
e many, varied and idiosyncratic when individual species are considere
d, there are nevertheless some basic general constraints and ground ru
les that make some species more extinction-prone than others. This pap
er reviews their implications for the ultimate and proximate causes of
extinction. Phenomena reviewed include: a positive correlation betwee
n local abundance and size of geographic range, putting some populatio
ns in 'double jeopardy'; smaller average range sizes in the tropics; m
etapopulation dynamic processes that can spread risk, but only if the
spatial correlation between fluctuations of conspecific populations is
low; the influence of body size and trophic position; and phylogeneti
c constraints on range sizes and abundance.