Itraconazole antifungal activity is investigated by agar diffusion tes
ts. In this study we have investigated the influence of sodium dioctyl
sulfosuccinate, an anionic surfactant, in Sabouraud dextrose agar at
different culture conditions on the itraconazole activity against Cand
ida albicans. The results demonstrated that it is possible to obtain c
leared and increased zones of inhibition and a good dosage/zone of inh
ibition correlation also in complex medium such as Sabouraud dextrose.