LACTATE-DEHYDROGENASE ISOZYMES IN UTERINE FLUID OF INFERTILE WOMEN

Electrophoretic studies revealed predominance of LDH isozymes (LDH(4) and LDH(5): M-isozymes) throughout the menstrual cycle in the uterine luminal fluid of both parous and infertile women. Parous women M-isozy mes maintain higher activity during phase I to phase III (early follic ular phase to ovulatory phase) than infertile women. During the post-o vulatory phase (phase IV) the M-isozyme shows lowest level in parous w omen. In contrast, during this phase (phase IV) to late-luteal phase ( phase VI) the M-isozymes show high activity in the fluid milieu of inf ertile women.