TREATMENT OF SOULIER-BOFFA SYNDROME WITH INTRAVENOUS IMMUNOGLOBULINS - POSSIBLE DISSOCIATION OF CLINICAL AND BIOLOGICAL EFFECTS

The treatment of the antiphospholipid syndrome with fetal loss (Soulie r-Boffa) is not clearly defined. We have treated 3 women with intraven ous-immunoglobulin alone or associated with aspirin, heparin or cortic osteroids. All three gave birth to live children. The biological resul ts showed in one case a disappearance of anticardiolipin antibodies, b ut in two others cases the level of antibodies is still high. These da te show that clinical and biological results can be different in Souli er-Boffa syndrome under treatment.