PLASMA THROMBOMODULIN, A MARKER OF ENDOTH ELIAL LESIONS - STUDY ON DERMATOMYOPOLYMYOSITIS AND LUPUS

Authors
MERCIE P SEIGNEUR M CONSTANS J DUFOURCQ P PRUVOST A BEYLOT C PELLEGRIN JL LONGYBOURSIER M BOISSEAU MR CONRI C
Citation
P. Mercie et al., PLASMA THROMBOMODULIN, A MARKER OF ENDOTH ELIAL LESIONS - STUDY ON DERMATOMYOPOLYMYOSITIS AND LUPUS, La Revue de medecine interne, 14(6), 1993, pp. 407-407
Citations number
NO
Categorie Soggetti
Medicine, General & Internal
Journal title
La Revue de medecine interne → ACNP
ISSN journal
02488663
Volume
14
Issue
6
Year of publication
1993
Pages
407 - 407
Database
ISI
SICI code
0248-8663(1993)14:6<407:PTAMOE>2.0.ZU;2-Q
Abstract
Variations of plasma thrombomodulin levels, which is a putative marker of endothelial damage, were measured in 23 cases of systemic lupus er ythematosus (without antiphospholipids and/or lupus anticoagulants) an d in 7 dermatopolymyositis. This parameter was significantly increased in dermatopolymyositis suggesting the involvement of ischemia in endo thelium injury. No change in plasma thrombomodulin levels was observed in patients with systemic lupus erythematosus.