P. Vanhille et al., ANTICYTOPLASMIC ANTIBODIES OF POLYMORPHON UCLEAR NEUTROPHILS AND GRANULOMATOUS ACUTE INTERSTITIAL NEPHRITIS, La Revue de medecine interne, 14(6), 1993, pp. 437-437
This report documents 2 patients where P-ANCA positivity (anti-MPO Ab)
was a feature of acute renal insufficiency produced by numerous inter
stitial necrotizing granulomas without segmental glomerulitis or angii
tis In both cases, immunosuppressive therapy lead to renal improvement
. These 2 cases may be considered as an unusual kidney-limited Wegener
's granulomatosis.