PREDOMINANCE OF THE SUBCLASS IGGL AMONG T HE ANTI-RO SSA ANTIBODIES, BUT NOT AMONG THE ANTI-LA SSB ANTIBODIES IN PRIMARY GOUGEROT-SJOGREN SYNDROME

Authors
MARAN R PENNEC YL DUEYMES M SHOENFELD Y YOUINOU P
Citation
R. Maran et al., PREDOMINANCE OF THE SUBCLASS IGGL AMONG T HE ANTI-RO SSA ANTIBODIES, BUT NOT AMONG THE ANTI-LA SSB ANTIBODIES IN PRIMARY GOUGEROT-SJOGREN SYNDROME, La Revue de medecine interne, 14(6), 1993, pp. 446-446
Citations number
NO
Categorie Soggetti
Medicine, General & Internal
Journal title
La Revue de medecine interne → ACNP
ISSN journal
02488663
Volume
14
Issue
6
Year of publication
1993
Pages
446 - 446
Database
ISI
SICI code
0248-8663(1993)14:6<446:POTSIA>2.0.ZU;2-B
Abstract
Isotype-specific enzyme-linked immunosorbent assays have been develope d to assess anti-Ro/SSA and anti-La/SSB IgG subclasses in 31 patients with primary Sjogren's syndrome. The anti-Ro/SSA antibody production w as largely restricted to IgG1, whilst the anti-La/SSB subclass distrib ution varied from one patient to another. IgG2 and IgG3 anti-La/SSB we re more frequent in those patients with extraglandular complications.