TAMOXIFEN AND THE ENDOMETRIUM - REVIEW OF 50 CASES OF ABNORMAL UTERINE BLEEDING

Authors
LEBOUEDEC G KAUFFMANN P CURE H FEILLEL V DAUPLAT J
Citation
G. Lebouedec et al., TAMOXIFEN AND THE ENDOMETRIUM - REVIEW OF 50 CASES OF ABNORMAL UTERINE BLEEDING, La Revue de medecine interne, 14(6), 1993, pp. 453-453
Citations number
NO
Categorie Soggetti
Medicine, General & Internal
Journal title
La Revue de medecine interne → ACNP
ISSN journal
02488663
Volume
14
Issue
6
Year of publication
1993
Pages
453 - 453
Database
ISI
SICI code
0248-8663(1993)14:6<453:TATE-R>2.0.ZU;2-M
Abstract
Fifty cases of abnormal uterine bleeding occured among women receiving tamoxifen for breast cancer have been investigated by hysteroscopy an d dilatation-curetage. The histopathologic findings were the following : atrophic mucosa (11 cases), hyperplasic mucosa or endometrial polyp s (34 cases), endometrial adenocarcinoma (5 cases). These results high light the potential estrogen-like property so-called paradoxical effec t of tamoxifen and its suggested oncogenic risk toward the endometrium .