7 patients suffering from localized scleroderma received high dose of
1,25 dihydroxycholecalciferol (1.25 gg/day). A significant improvement
was observed within 2 to 24 months. Skin extensibility was significan
tly increased after treatment. 1,25 dihydroxycholecalciferol could be
beneficial in patients with localized scleroderma.