SIGNIFICANCE OF COMBINED CYCLOPHOSPHAMIDE AND PREDNISONE AS 1ST-LINE TREATMENT OF NON-HEMOPHILIC PATIENTS WITH FACTOR-VIII INHIBITOR

Authors
BERRUT G SHOAAY I DUPUIS JM MAIGRE M FRESSINAUD P FRESSINAUD E
Citation
G. Berrut et al., SIGNIFICANCE OF COMBINED CYCLOPHOSPHAMIDE AND PREDNISONE AS 1ST-LINE TREATMENT OF NON-HEMOPHILIC PATIENTS WITH FACTOR-VIII INHIBITOR, La Revue de medecine interne, 14(6), 1993, pp. 503-503
Citations number
NO
Categorie Soggetti
Medicine, General & Internal
Journal title
La Revue de medecine interne → ACNP
ISSN journal
02488663
Volume
14
Issue
6
Year of publication
1993
Pages
503 - 503
Database
ISI
SICI code
0248-8663(1993)14:6<503:SOCCAP>2.0.ZU;2-D
Abstract
Seven non haemophilic patients with acquired Factor VIll inhibitor wer e treated as first line therapy with a cyclophosphamide - prednisone c ombination. In 6 patients complete suppression of the inhibitor was ob served within 9 to 60 days. Relapses occurred in two patients and this treatment was again successfull. In the 7th patient a significant dec rease of the inhibitor was observed allowing porcine Factor VIII repla cement therapy if desired.