THIOLS, UNSYMMETRICAL SULFIDES AND THIOACETALS FROM THE NEW REAGENT -TRIISOPROPYLSILANETHIOL

Authors
MIRANDA EI DIAZ MJ ROSADO I SODERQUIST JA
Citation
Ei. Miranda et al., THIOLS, UNSYMMETRICAL SULFIDES AND THIOACETALS FROM THE NEW REAGENT -TRIISOPROPYLSILANETHIOL, Tetrahedron letters, 35(20), 1994, pp. 3221-3224
Citations number
24
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
20
Year of publication
1994
Pages
3221 - 3224
Database
ISI
SICI code
0040-4039(1994)35:20<3221:TUSATF>2.0.ZU;2-S
Abstract
Triisopropylsilanethiol (HSTIPS, 1), easily prepared in 98% yield from H2S and TIPSCl, is efficiently alkylated in a selective manner with 1 degrees and 2 degrees alkyl halides or tosylates through its potassiu m thiolate (2c) to provide RSTIPS (3) in excellent yields. Compound 3 provides a convenient source of alkanethiols (4), unsymmetrical dialky l sulfides (5) and thioacetals (6).