AN EFFICIENT ASYMMETRIC-SYNTHESIS OF -3-AMINO-2,3,4,5-TETRAHYDRO-1H-[1]BENZAZEPIN-2-ONE

Authors
ARMSTRONG JD ENG KK KELLER JL PURICK RM HARTNER FW CHOI WB ASKIN D VOLANTE RP
Citation
Jd. Armstrong et al., AN EFFICIENT ASYMMETRIC-SYNTHESIS OF -3-AMINO-2,3,4,5-TETRAHYDRO-1H-[1]BENZAZEPIN-2-ONE, Tetrahedron letters, 35(20), 1994, pp. 3239-3242
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
20
Year of publication
1994
Pages
3239 - 3242
Database
ISI
SICI code
0040-4039(1994)35:20<3239:AEAO->2.0.ZU;2-1
Abstract
Two approaches for the asymmetric preparation of (-)- or (+)- alpha-am inobenzlactam 1 are described. One route is based on the asymmetric hy drogenation of enamide 5 and the other on the racemization/resolution of (+/-)-1.