POLYSIALIC ACID EXPRESSION IN THE SALAMANDER RETINA IS INDUCIBLE BY THYROXINE

Authors
BECKER CG BECKER T SCHMIDT A ROTH G
Citation
Cg. Becker et al., POLYSIALIC ACID EXPRESSION IN THE SALAMANDER RETINA IS INDUCIBLE BY THYROXINE, Developmental brain research, 79(1), 1994, pp. 140-146
Citations number
31
Categorie Soggetti
Neurosciences
Journal title
Developmental brain research → ACNP
ISSN journal
01653806
Volume
79
Issue
1
Year of publication
1994
Pages
140 - 146
Database
ISI
SICI code
0165-3806(1994)79:1<140:PAEITS>2.0.ZU;2-M
Abstract
Polysialylation of the neural cell adhesion molecule (NCAM) in the ret ina of Pleurodeles waltl is up-regulated during metamorphosis. Incubat ion of larvae in thyroxine permanently induced polysialic acid express ion in the retina in a concentration-dependent but age-independent man ner within 3 days of incubation (3 X 10(-7) M). Retinoic acid had no e ffect. This suggests direct hormonal regulation of a post-translationa l modification of NCAM in the amphibian retina.