ACCUMULATION AND INTRACELLULAR FATE OF TELLURITE IN TELLURITE-RESISTANT ESCHERICHIA-COLI - A MODEL FOR THE MECHANISM OF RESISTANCE

Authors
LLOYDJONES G OSBORN AM RITCHIE DA STRIKE P HOBMAN JL BROWN NL ROUCH DA
Citation
G. Lloydjones et al., ACCUMULATION AND INTRACELLULAR FATE OF TELLURITE IN TELLURITE-RESISTANT ESCHERICHIA-COLI - A MODEL FOR THE MECHANISM OF RESISTANCE, FEMS microbiology letters, 118(1-2), 1994, pp. 113-119
Citations number
23
Categorie Soggetti
Microbiology
Journal title
FEMS microbiology letters → ACNP
ISSN journal
03781097
Volume
118
Issue
1-2
Year of publication
1994
Pages
113 - 119
Database
ISI
SICI code
0378-1097(1994)118:1-2<113:AAIFOT>2.0.ZU;2-O
Abstract
The tellurite accumulation properties of three Escherichia coil strain s containing different tellurium-resistance determinants of Gram-negat ive origin, from plasmids pMER610, pHH1508a and RK2, were compared. In all three cases membrane-associated tellurium crystallization was obs erved, and neither reduced uptake nor increased export contributed to the resistance. Specific membrane-proximal reduction is proposed as th e mechanism of resistance to tellurite coded by all three determinants , despite their lack of sequence homology.