EFFECT OF GROWTH TEMPERATURE ON COMPLEMENT-MEDIATED KILLING OF MESOPHILIC AEROMONAS SPP SEROTYPE O 34/

Authors
MERINO S ALVAREZ D HERNANDEZALLES S TOMAS JM
Citation
S. Merino et al., EFFECT OF GROWTH TEMPERATURE ON COMPLEMENT-MEDIATED KILLING OF MESOPHILIC AEROMONAS SPP SEROTYPE O 34/, FEMS microbiology letters, 118(1-2), 1994, pp. 163-166
Citations number
16
Categorie Soggetti
Microbiology
Journal title
FEMS microbiology letters → ACNP
ISSN journal
03781097
Volume
118
Issue
1-2
Year of publication
1994
Pages
163 - 166
Database
ISI
SICI code
0378-1097(1994)118:1-2<163:EOGTOC>2.0.ZU;2-B
Abstract
Mesophilic Aeromonas spp. strains (serotype 0:34) showed sensitivity t o complement-mediated killing when they were cultivated at 37 degrees C (serum-sensitive) but not when they were cultivated at 20 degrees C (serum-resistant). These strains produced smooth lipopolysaccharide wh en they were grown at 20 degrees C and rough lipolysaccharide when cul tivated at 37 degrees C. The reason for the resistance to complement-m ediated killing could be that C3b is rapidly degraded (possibly becaus e it is bound far from the cell membrane), consequently the lytic comp lex (C5b-9) is not formed.