NONINVASIVE BLOOD-GLUCOSE SENSORS BASED ON NEAR-INFRARED SPECTROSCOPY

Research into noninvasive devices for self-monitoring of blood glucose is mainly based on near-infrared spectroscopy. Such a device is parti cularly desirable in the intensive therapy of patients with diabetes m ellitus to achieve optimal metabolic control through frequent glucose testing. The state of noninvasive assay technology is presented. Using diffuse reflectance spectra of mucous lip tissue has advantages and d rawbacks compared with tissue transmittance experiments. Different app roaches have been proposed in the patent literature; however, current technology requires further significant improvements, particularly wit hin the lower normal and hypoglycemic glucose concentration ranges.