M. Adamczyk et al., IMMUNOASSAY REAGENTS FOR PSYCHOACTIVE-DRUGS .4. QUANTITATIVE-DETERMINATION OF AMITRIPTYLINE AND NORTRIPTYLINE BY FLUORESCENCE POLARIZATION IMMUNOASSAY, Therapeutic drug monitoring, 16(3), 1994, pp. 298-311
Methods for the quantitative determination of amitriptyline and nortri
ptyline by fluorescence polarization immunoassay (FPIA) is described.
One immunoassay allows for the accurate quantification of amitriptylin
e in the presence of nortriptyline while the second immunoassay allows
for the accurate quantification of nortriptyline in the presence of a
mitriptyline.