MULTIPLE SUBPIAL TRANSECTIONS IN THE LANGUAGE CORTEX

Citation
O. Devinsky et al., MULTIPLE SUBPIAL TRANSECTIONS IN THE LANGUAGE CORTEX, Brain, 117, 1994, pp. 255-265
Citations number
23
Categorie Soggetti
Neurosciences
Journal title
BrainACNP
ISSN journal
00068950
Volume
117
Year of publication
1994
Part
2
Pages
255 - 265
Database
ISI
SICI code
0006-8950(1994)117:<255:MSTITL>2.0.ZU;2-R
Abstract
Multiple subpial transections (MST) were made in language cortex in th ree patients with medically refractory partial epilepsy. All patients were mapped with extra-operative stimulation using subdural grids over the dominant temporal, frontal and parietal convexity. Two patients h ad anterior temporal lobectomy and MST in posterior language cortex. O ne patient who had undergone a previous frontal tumour resection had o nly MST over the frontoparietal convexity, including frontal and parie tal language areas. Both patients with MST in the posterior language c ortex had postoperative language dysfunction, which had improved signi ficantly by 9 months after surgery, The patient with MST in frontopari etal language areas had improved language functions immediately postop eratively. The two men with anterior temporal lobectomies and MST are seizure-free at 1 year follow-up and the woman with fronto-parietal MS T has had a > 70% reduction in seizure frequency at 1 year follow-up.