PIECEWISE EXPONENTIAL SURVIVAL CURVES WITH SMOOTH TRANSITIONS

Authors
ZELTERMAN D GRAMBSCH PM LE CT MA JZ CURTSINGER JW
Citation
D. Zelterman et al., PIECEWISE EXPONENTIAL SURVIVAL CURVES WITH SMOOTH TRANSITIONS, Mathematical biosciences, 120(2), 1994, pp. 233-250
Citations number
32
Categorie Soggetti
Mathematical Methods, Biology & Medicine","Mathematics, Miscellaneous","Biology Miscellaneous
Journal title
Mathematical biosciences → ACNP
ISSN journal
00255564
Volume
120
Issue
2
Year of publication
1994
Pages
233 - 250
Database
ISI
SICI code
0025-5564(1994)120:2<233:PESCWS>2.0.ZU;2-1
Abstract
Several models of a population survival curve composed of two piecewis e exponential distributions are developed. In one formulation the haza rd rate changes at a point that is an unobservable random variable tha t varies between individuals. The population hazard function may decre ase with age even when all individuals' hazards are increasing. In a s econd formulation, the population hazard function is modeled directly. Several models are fit to the survival history of a cohort of 5751 hi ghly inbred male Drosophila melanogaster and the British coal mining d isaster data.