MYXOVIRUS AND PARAMYXOVIRUS SURFACE-STRUCTURES - ANTIGENIC AND FUNCTIONAL-STUDIES

The presence of specific carbohydrates on viral surface structures, de veloping an important role in their biological processes, was analysed using Newcastle Disease Viruses (SO-93, B1 and La Sota strains) ind I nfluenza virus (A/Influenza/PR/8/34 (H1N1) strain) as models. Virus sa mples were concentrated by sedimentation process, purified by tartrate gradient, they were washed through another sedimentation step and eva luated by their protein content, hemagglutination titer and carbohydra te residues. This study developed with lectins and specific sugars cou ld show carbohydrates as essential elements of virus surface structure s, which were revealed for inhibition of precipitation lines among con canavalin A and Newcastle Disease Virus specific serum.