This contribution to Zadoks' liber amicorum reviews the developments i
n quantitative epidemiology during the last decades. It elucidates the
progress in this field and shows how empirical crop protection with m
any phenomenological aspects transformed into a science-based (inter)d
iscipline. The availability of experimental tools and the rapid develo
pment and introduction of computers enabled the application of systems
approaches which stimulated a revolution in thinking and caused a con
siderable improvement of strategic and tactical decision making in cro
p protection. Zadoks played a crucial role in that development.