SYNTHESIS AND CHARACTERIZATION OF BIOLOGICALLY-ACTIVE OXOVANADIUM(V) AND MANGANESE(II) COMPLEXES OF SEMICARBAZONES

Several new complexes of oxovandium(V) and manganese(II) with the mono basic bidentate ligands 2-acetylnaphthalene semicarbazone, 2-acetylthi ophene semicarbazone, 2-acetylfuran semicarbazone and 2-acetylpyridine semicarbazone have been prepared and characterized by elemental analy sis, magnetic moments, IR, H-1 NMR and electronic spectral studies. Th e complexes were monomeric and non-electrolytes. A probable tetracoord inated tetrahedral geometry for manganese complexes and a pentacoordin ated distorted trigonal bipyramidal and hexacoordinated octahedral geo metries for 1:1 and 1:2 (M:L) oxovanadium complexes, respectively, hav e been proposed. Some representative complexes of manganese and oxovan adium are found to have remarkable antifungal and antibacterial activi ties.