K. Bleicher et E. Bayer, VARIOUS FACTORS INFLUENCING THE SIGNAL INTENSITY OF OLIGONUCLEOTIDES IN ELECTROSPRAY MASS-SPECTROMETRY, Biological mass spectrometry, 23(6), 1994, pp. 320-322
The quality of electrospray mass spectra of oligonucleotides often suf
fers from the low signal intensity and clustering with metal ions. Thi
s sometimes makes an exact determination of the molecular masses impos
sible. We describe here several factors contributing to these effects
and show some means for their improvement.