In this paper, quantitative tomographic reconstructions of biological
tissue are presented. First, the experimental setup and a hybrid filte
red backpropagation (FBP) technique are briefly described. Using this
technique, which includes exact backpropagation of data prior to recon
struction by means of the classical FBP algorithm, quantitative veloci
ty maps of relatively large biological objects can be obtained. Since
the FBP algorithm is based on a first-order scattering approximation,
the deteriorating effects of higher-order scattering in diffraction to
mography are also discussed. The higher-order scattering limits the si
ze of the biological object to a few centimeters. (C) 1994 Academic Pr
ess, Inc.