Kg. Nilsson et al., EARLY FAILURE OF HYDROXYAPATITE-COATING IN TOTAL KNEE ARTHROPLASTY - A CASE-REPORT, Acta orthopaedica Scandinavica, 65(2), 1994, pp. 212-214
We observed early loosening of a hydroxyapatite-coated tibial componen
t in a total knee arthroplasty in a randomized study comparing HA-coat
ing with cement fixation. Symptoms of loosening started 8 weeks after
surgery. Roentgen stereophotogrammetric analysis revealed stability du
ring the initial 6 weeks followed by a pronounced subsidence up to 6 m
onths after surgery when revision was done. At revision, the HA-coatin
g was found to have separated from the medial part of the tibial compo
nent. The synovium was abundant with macrophages and multinucleated gi
ant cells containing HA-crystals. Overloading of the prosthesis and su
boptimal quality of the HA-coating was believed to have caused the loo
sening process.