A USEFUL METHOD FOR THE PREPARATION OF FULLY PROTECTED PEPTIDE ACIDS AND ESTERS

Authors
PICHETTE A VOYER N LAROUCHE R MEILLON JC
Citation
A. Pichette et al., A USEFUL METHOD FOR THE PREPARATION OF FULLY PROTECTED PEPTIDE ACIDS AND ESTERS, Tetrahedron letters, 38(8), 1997, pp. 1279-1282
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
8
Year of publication
1997
Pages
1279 - 1282
Database
ISI
SICI code
0040-4039(1997)38:8<1279:AUMFTP>2.0.ZU;2-L
Abstract
Resin bound peptides can be cleaved from the Kaiser oxime resin using various oxygen nucleophiles (H2O, CH3OH, PhCH(2)OH) with DBU. Fully pr otected peptide acids and eaters are obtained rapidly and with good yi elds using this new method of cleavage. (C) 1997 Elsevier Science Ltd.