ENZYMATIC INTRODUCTION OF N-HETEROCYCLIC AND AS-CONTAINING HEAD GROUPS INTO GLYCEROPHOSPHOLIPIDS

Authors
HIRCHE F SCHIERHORN A SCHERER G ULBRICHHOFMANN R
Citation
F. Hirche et al., ENZYMATIC INTRODUCTION OF N-HETEROCYCLIC AND AS-CONTAINING HEAD GROUPS INTO GLYCEROPHOSPHOLIPIDS, Tetrahedron letters, 38(8), 1997, pp. 1369-1370
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
8
Year of publication
1997
Pages
1369 - 1370
Database
ISI
SICI code
0040-4039(1997)38:8<1369:EIONAA>2.0.ZU;2-J
Abstract
The synthesis of six new glycerophospholipids with choline-analogous h ead groups by enzymatic transphosphatidylation with phospholipase D is described. Starting from 1,2-dioleoyl-sn-glycero-3-phosphocholine pri mary or secondary N-heterocyclic alcohols and (2-hydroxyethyl) trimeth ylarsonium were substituted for choline in two-phase systems. (C) 1997 Elsevier Science Ltd.