ASYMMETRIC AMINO-HYDROXYLATION OF DIENYLSILANES - AN EFFICIENT ROUTE TO AMINO-CYCLITOLS

Authors
ANGELAUD R LANDAIS Y SCHENK K
Citation
R. Angelaud et al., ASYMMETRIC AMINO-HYDROXYLATION OF DIENYLSILANES - AN EFFICIENT ROUTE TO AMINO-CYCLITOLS, Tetrahedron letters, 38(8), 1997, pp. 1407-1410
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
8
Year of publication
1997
Pages
1407 - 1410
Database
ISI
SICI code
0040-4039(1997)38:8<1407:AAOD-A>2.0.ZU;2-X
Abstract
Sharpless asymmetric amino-hydroxylation of a silyl-2,5-cyclohexadiene occurs with complete regio- and diastereocontrol. An enantioselectivi ty of up td 68% e.e. was also observed. An application of the methodol ogy to the synthesis of relevant examples of aminocyclitols is describ ed. (C) 1997 Elsevier Science Ltd.