M. Delhaye et al., STEROID AND ALCOHOL CELIAC PLEXUS BLOCK IN CHRONIC-PANCREATITIS, European journal of gastroenterology & hepatology, 6(6), 1994, pp. 553-558
Objective: To evaluate the indications, immediate benefit, patient out
come and side effects of either alcohol or steroid coeliac plexus bloc
k in a subset of patients with persistent severe pain due to chronic p
ancreatitis. Design: We retrospectively analysed 14 patients with pain
ful chronic pancreatitis who underwent coeliac plexus block from March
1992 to September 1993. Patients: Patients were ill for a mean of 7 y
ears, and were treated for a mean of 3.3 years. Prior surgery was perf
ormed in six patients, while 13 underwent prior endoscopic management,
all continued to have debilitating pain, and were unresponsive to ora
l medication and to appropriate ductal drainage procedures. Methods: A
total of 27 coeliac plexus blocks were performed using the posterior
approach. Depot steroid (n = 17) or alcohol (n = 10), diluted in local
anaesthetic, were injected under fluoroscopic control. Results: Compl
ete resolution or significant decrease in pain was recorded after 24 h
by all patients. Duration of significant pain relief ranged from 2 da
ys to more than 7 months (mean 2 months) after steroid coeliac plexus
block, and from 4 days to 14 months (mean 4 months) after alcohol coel
iac plexus block. Pain relief lasting at least 1 month was obtained in
56% of steroid and in 70% of alcohol coeliac plexus blocks. In six pa
tients, repeating the block produced longer lasting pain relief than a
fter the first procedure. Conclusions: Coeliac plexus block is a poten
tial component of the therapeutic armamentarium, giving selected chron
ic pancreatitis patients with intractable pain a few months of pain-fr
ee life.