STEREOSELECTIVE ACCESS TO TRANS-2,5-DISUBSTITUTED PYRROLIDINE DERIVATIVES BY NUCLEOPHILIC-ADDITION TO BICYCLIC N-ACYLIMINIUM ION

Authors
DHIMANE H VANUCCI C LHOMMET G
Citation
H. Dhimane et al., STEREOSELECTIVE ACCESS TO TRANS-2,5-DISUBSTITUTED PYRROLIDINE DERIVATIVES BY NUCLEOPHILIC-ADDITION TO BICYCLIC N-ACYLIMINIUM ION, Tetrahedron letters, 38(8), 1997, pp. 1415-1418
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
8
Year of publication
1997
Pages
1415 - 1418
Database
ISI
SICI code
0040-4039(1997)38:8<1415:SATTPD>2.0.ZU;2-0
Abstract
5-Alkoxy-pyrroloxazolidin-3-ones I were stereoselectively prepared fro m (S)-pyroglutamic acid Treatment of I with a Lewis acid generated in situ the N-acyliminium 2, which was trapped by various x-nucleophiles leading selectively to Irans pyrrolidine derivatives 3. (C) 1997 Publi shed by Elsevier Science Ltd.