Dd. Yuh et al., PRIMARY CARDIAC LYMPHOMA TREATED WITH ORTHOTOPIC HEART-TRANSPLANTATION - A CASE-REPORT, The Journal of heart and lung transplantation, 13(3), 1994, pp. 538-542
Primary lymphoma of the heart is an extremely rare tumor. It is associ
ated with a high mortality rate because of the advanced stage of myoca
rdial involvement at initial presentation. Conventional surgical and m
edical treatments have not met with much success. This article reports
the first case of primary cardiac lymphoma treated with orthotopic he
art transplantation. The patient had hemodynamically significant sever
e acute rejection, neutropenic sepsis, and tumor recurrence during the
late postoperative period, illustrating the difficulties associated w
ith concomitant immunosuppression and tumor chemotherapy. Unfortunatel
y, the patient died after a period of remission. Our approach to the i
ntegration of immunosuppression with chemotherapy, posttransplantation
follow-up, and complications is discussed.