Ap. Loibner et al., AUTOMATED GLUCOSE MEASUREMENT WITH MICROSTRUCTURED THIN-LAYER BIOSENSORS FOR THE CONTROL OF FERMENTATION PROCESSES, Sensors and actuators. B, Chemical, 19(1-3), 1994, pp. 603-606
A system for the on-line measurement and control of glucose levels in
fermentation of animal cell culture was tested for long-term applicabi
lity. The system consists of an aseptic sampling system, a novel type
of thin-layer biosensor incorporated in a flow-injection-analysis (FIA
) system and a software package for automation of the sampling and ana
lysis devices.